JAGLX
ActiveJanus Henderson Global Life Sciences Fund
Category: US Equity (9,528 funds)
Expense Ratio
0.92%
Annual Cost per $10K
$92.00
30-Year Fee Drag per $10K
$17,373
at 7% annual return
Fund Type
Mutual Fund
Active
Trailing 12-Month
-3.58%
Asset Allocation
US Equity
81%Intl Equity
10%Other
9%Fee Comparison
JAGLX
0.92%US Equity average
1.06%US Equity cheapest
0.00%Index benchmark
0.03%13% cheaper than category average
Historical Returns
Monthly total returns (dividends reinvested) from SEC N-PORT filings · As of December 2025 · Updated quarterly
+34.26%3Y
Compare to
Fee Impact Calculator
$
%
JAGLX at 0.92%$293,748
At index rates (0.03%)$377,424
Zero fees (theoretical)$380,613
Total fee drag$86,864
Cost vs index fund−$83,676
Similar Funds (100)
Ranked by allocation similarity weighted by fund size · Returns (dividends reinvested) from SEC N-PORT filings · As of December 2025
| Ticker | Name | ER |
|---|---|---|
| JAGLX | Janus Henderson Global Life Sciences Fund | 0.92% |
| AICCX | Investment Co of America | 0.32% |
| AFMFX | American Mutual Fund | 0.57% |
| DODGX | Dodge & Cox Stock Fund$1M min | 0.51% |
| AMCFX | AMCAP Fund | 0.43% |
| MEIAX | MFS Value Fund | 0.79% |
| AAGTX | American Funds 2040 Target Date Retirement Fund | 0.68% |
| PEIYX | Putnam Large Cap Value Fund | 0.63% |
| PMBJX | MidCap Fund | 0.80% |
| TRUZX | T. Rowe Price New Horizons Fund, Inc. | 0.64% |
| CGPAX | American Funds Growth Portfolio | 0.99% |
| AAHTX | American Funds 2045 Target Date Retirement Fund | 0.69% |
| TRMIX | T. Rowe Price Mid-Cap Value Fund, Inc. | 0.71% |
| FOCKX | Fidelity OTC Portfolio | 1.05% |
| AALTX | American Funds 2050 Target Date Retirement Fund | 0.69% |
| TRQZX | T. Rowe Price Mid-Cap Growth Fund, Inc. | 0.61% |
| FFOJX | Select Technology Portfolio | 0.91% |
| FZANX | Fidelity Advisor New Insights Fund | 0.53% |
| MCPRX | MFS Mid Cap Growth Fund | 1.02% |
| FRDPX | Franklin Rising Dividends Fund | 0.83% |
| FKDNX | Franklin Dynatech Fund | 0.82% |
| MVCKX | MFS Mid Cap Value Fund | 0.62% |
| WFPRX | Allspring Special Mid Cap Value Fund | 0.70% |
| TRZDX | T. Rowe Price Dividend Growth Fund, Inc. | 0.49% |
| BLPAX | American Funds Moderate Growth and Income Portfolio | 0.93% |
| BBVLX | Bridge Builder Large Cap Value Fund | 0.23% |
| THISX | T. Rowe Price Health Sciences Fund, Inc. | 0.67% |
| TRZQX | T. Rowe Price Equity Income Fund | 0.53% |
| FIFRX | Franklin Growth Fund | 0.46% |
| DDFIX | Invesco Diversified Dividend Fund | 1.07% |
| JMGFX | JPMorgan Mid Cap Growth Fund | 1.09% |
| TRZZX | T. Rowe Price Small-Cap Stock Fund, Inc. | 0.74% |
| VAFAX | Invesco American Franchise Fund | 0.93% |
| PNOBX | Putnam Sustainable Leaders Fund | 0.88% |
| DFSVX | U.S. SMALL CAP VALUE PORTFOLIO$1M min | 0.31% |
| FGIDX | Fidelity Growth and Income Portfolio | 0.46% |
| QVG2Q | VIP Growth Portfolio | 0.66% |
| ACCLX | Mid Cap Value Fund | 0.62% |
| PRWAX | T. Rowe Price All-Cap Opportunities Fund | 0.79% |
| SOXX | iShares Semiconductor ETF | 0.34% |
| FDGFX | Fidelity Dividend Growth Fund | 1.16% |
| FZAFX | Fidelity Advisor Equity Growth Fund | 0.55% |
| ACSHX | Invesco Comstock Fund | 0.51% |
| POAGX | PRIMECAP Odyssey Aggressive Growth Fund | 0.66% |
| FFDKX | Fidelity Fund | 0.42% |
| POGRX | PRIMECAP Odyssey Growth Fund | 0.66% |
| LCBEX | ClearBridge Dividend Strategy Fund | 0.66% |
| FSPHX | Select Health Care Portfolio | 0.63% |
| FCAKX | Fidelity Capital Appreciation Fund | 0.66% |
| FVD | First Trust Value Line Dividend Index Fund | 0.61% |
| FADTX | Fidelity Advisor Technology Fund | 0.55% |
| BGRUX | BARON GROWTH FUND | 1.09% |
| TRZVX | T. Rowe Price Small-Cap Value Fund, Inc. | 0.64% |
| ARKK | ARK Innovation ETF | 0.75% |
| FHZTX | Fidelity Large Cap Stock Fund | 1.02% |
| HQIFX | THE HARTFORD EQUITY INCOME FUND | 0.64% |
| JLVMX | JPMorgan Large Cap Value Fund | 0.93% |
| POSKX | PRIMECAP Odyssey Stock Fund | 0.67% |
| XFBRX | VIP Mid Cap Portfolio | 0.82% |
| GOGFX | Victory Sycamore Small Company Opportunity Fund | 1.23% |
| ACSCX | Small Cap Value Fund | 0.73% |
| FCAGX | Fidelity Small Cap Growth Fund | 0.92% |
| PARWX | Parnassus Value Equity Fund | 0.88% |
| PRDSX | T. Rowe Price Integrated U.S. Small-Cap Growth Equity Fund | 0.79% |
| FDSVX | Fidelity Growth Discovery Fund | 0.62% |
| TMSIX | THRIVENT MID CAP STOCK FUND | 0.74% |
| TRSSX | T. Rowe Price Institutional Small-Cap Stock Fund$1M min | 0.66% |
| MFRKX | MFS Research Fund | 0.46% |
| MITJX | Massachusetts Investors Trust | 0.38% |
| POLRX | Polen Growth Fund | 1.22% |
| HFMVX | THE HARTFORD MIDCAP FUND | 0.73% |
| AMAGX | Amana Growth Fund | 0.61% |
| LAFVX | LORD ABBETT AFFILIATED FUND INC | 0.39% |
| FDSSX | Fidelity Stock Selector Fund | 0.49% |
| FCPVX | Fidelity Small Cap Value Fund | 1.20% |
| ACGIX | Invesco Growth and Income Fund | 0.78% |
| MRERX | MFS Core Equity Fund | 0.88% |
| ISTNX | Macquarie Science and Technology Fund | 1.42% |
| ICEQX | Macquarie Core Equity Fund | 0.74% |
| ACFLX | Focused Large Cap Value Fund | 1.09% |
| WGROX | Wasatch Core Growth Fund | 1.17% |
| LCSSX | ClearBridge Select Fund | 0.98% |
| FRCSX | Franklin Small Cap Value Fund | 0.60% |
| HIACX | HARTFORD CAPITAL APPRECIATION HLS FUND | 0.67% |
| FMILX | Fidelity New Millennium Fund | 0.76% |
| NICSX | Nicholas Fund, Inc. | 0.70% |
| JAAGX | Janus Henderson Enterprise Portfolio$1M min | 0.97% |
| FCDAX | Fidelity Stock Selector Small Cap Fund | 0.85% |
| FBIOX | Select Biotechnology Portfolio | 0.63% |
| MGRPX | GROWTH PORTFOLIO | 0.52% |
| QTEC | First Trust NASDAQ-100-Technology Sector Index Fund | 0.55% |
| HIADX | HARTFORD DIVIDEND AND GROWTH HLS FUND | 0.66% |
| JLCNX | Fundamental Large Cap Core Fund | 0.65% |
| LAMHX | Lord Abbett Dividend Growth Fund | 0.59% |
| FACDX | Fidelity Advisor Health Care Fund | 0.68% |
| FVDFX | Fidelity Value Discovery Fund | 0.77% |
| APDMX | Artisan Mid Cap Fund | 1.05% |
| SGRAX | Allspring Growth Fund | 1.15% |
| FGSLX | Fidelity Growth Strategies Fund | 0.61% |
| ASPZX | ALGER SPECTRA FUND | 1.19% |
| LADCX | LORD ABBETT DEVELOPING GROWTH FUND INC | 0.94% |
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