LYFAX
ActiveAlphaCentric Life Sciences and Healthcare Fund
Category: US Equity (9,528 funds)
Expense Ratio
1.71%
Annual Cost per $10K
$171.00
30-Year Fee Drag per $10K
$29,175
at 7% annual return
Fund Type
Mutual Fund
Active
Trailing 12-Month
-1.11%
Asset Allocation
US Equity
70%Intl Equity
27%Cash
3%Fee Comparison
LYFAX
1.71%US Equity average
1.06%US Equity cheapest
0.00%Index benchmark
0.03%61% more expensive than category average
Historical Returns
Monthly total returns (dividends reinvested) from SEC N-PORT filings · As of December 2025 · Updated quarterly
+20.82%3Y
Compare to
Fee Impact Calculator
$
%
LYFAX at 1.71%$234,738
At index rates (0.03%)$377,424
Zero fees (theoretical)$380,613
Total fee drag$145,875
Cost vs index fund−$142,686
Similar Funds (100)
Ranked by allocation similarity weighted by fund size · Returns (dividends reinvested) from SEC N-PORT filings · As of December 2025
| Ticker | Name | ER |
|---|---|---|
| LYFAX | AlphaCentric Life Sciences and Healthcare Fund | 1.71% |
| QCSTFX | College Retirement Equities Fund - Stock Account | — |
| FKALX | Federated Hermes Kaufmann Small Cap Fund | 1.36% |
| SVAAX | Federated Hermes Strategic Value Dividend Fund | 1.06% |
| OWLSX | Old Westbury Large Cap Strategies Fund | 1.09% |
| QCGLFX | College Retirement Equities Fund - Global Equities Account | — |
| FNNEX | New Economy Fund | 0.47% |
| VGHAX | VANGUARD HEALTH CARE FUND | 0.32% |
| KAUAX | Federated Hermes Kaufmann Fund | 1.96% |
| FEEFX | American Funds Fundamental Investors | 0.34% |
| DODGX | Dodge & Cox Stock Fund$1M min | 0.51% |
| TTMIX | T. Rowe Price Communications & Technology Fund | 0.67% |
| AAHTX | American Funds 2045 Target Date Retirement Fund | 0.69% |
| AALTX | American Funds 2050 Target Date Retirement Fund | 0.69% |
| AAMTX | American Funds 2055 Target Date Retirement Fund | 0.70% |
| GSKPX | Goldman Sachs Tax-Advantaged Global Equity Portfolio | 1.22% |
| CGLGX | American Funds Growth and Income Portfolio | 0.92% |
| MGISX | GLOBAL FRANCHISE PORTFOLIO | 0.83% |
| PGTIX | T. Rowe Price Global Technology Fund, Inc. | 0.78% |
| JAFVX | Strategic Equity Allocation Trust | 0.92% |
| PSGFX | SAM Strategic Growth Portfolio | 1.07% |
| AMANX | Amana Income Fund | 1.01% |
| BGSAX | BlackRock Technology Opportunities Fund | 1.92% |
| AANTX | American Funds 2060 Target Date Retirement Fund | 0.72% |
| AAGTX | American Funds 2040 Target Date Retirement Fund | 0.68% |
| PGROX | BNY Mellon Worldwide Growth Fund, Inc. | 1.13% |
| FSELX | Select Semiconductors Portfolio | 0.62% |
| GQEFX | GMO Quality Fund | 0.42% |
| ECHSX | Eaton Vance Worldwide Health Sciences Fund | 1.18% |
| EAGL | Eagle Capital Select Equity ETF | 0.80% |
| VHGEX | VANGUARD GLOBAL EQUITY FUND | 0.39% |
| TAAKX | Transamerica Asset Allocation - Growth Portfolio | 1.06% |
| VGELX | VANGUARD ENERGY FUND | 0.45% |
| CGGEX | American Funds Global Growth Portfolio | 1.07% |
| CFIPX | Franklin Global Equity Fund | 1.55% |
| DGEIX | GLOBAL EQUITY PORTFOLIO$1M min | 0.26% |
| GCOZX | Moderately Aggressive Allocation Fund | 1.05% |
| NBFAX | Neuberger Berman Focus Fund | 1.12% |
| GQRPX | GQG PARTNERS GLOBAL QUALITY EQUITY FUND | 0.70% |
| PRJAX | PGIM Jennison Global Opportunities Fund | 1.08% |
| ALFVX | Lord Abbett Alpha Strategy Fund | 1.13% |
| FDVLX | Fidelity Value Fund | 0.68% |
| FLPCX | Fidelity Low-Priced Stock Fund | 1.40% |
| YACKX | AMG Yacktman Fund$1M min | 0.62% |
| MIGNX | MFS Massachusetts Investors Growth Stock Fund | 0.37% |
| GMHZX | MyDestination 2035 Fund | 0.75% |
| RMLPX | Recurrent MLP & Energy Infrastructure Fund$1M min | 1.10% |
| BEGRX | Franklin Mutual Beacon Fund | 1.27% |
| DLHAX | Macquarie Healthcare Fund | 1.46% |
| LYFCX | AlphaCentric Life Sciences and Healthcare Fund | 1.71% |
| PGIRX | Polen Global Growth Fund | 1.26% |
| CPCLX | Calamos Phineus Long/Short Fund | 2.44% |
| VVOAX | Invesco Value Opportunities Fund | 1.27% |
| FKMCX | Fidelity Mid-Cap Stock Fund | 1.69% |
| FMSHX | Franklin Mutual Shares Fund | 0.70% |
| FHCLX | Select Health Care Portfolio | — |
| WFPCX | Allspring Special Mid Cap Value Fund | 1.87% |
| GMFZX | MyDestination 2045 Fund | 0.72% |
| RPFGX | Davis Financial Fund | 0.94% |
| PCHSX | Putnam Global Health Care Fund | 1.04% |
| TCLPX | Nuveen Lifecycle 2050 Fund | 0.69% |
| TGIPX | T. Rowe Price Spectrum Moderate Growth Allocation Fund | 0.64% |
| RYTRX | Royce Small-Cap Total Return Fund | 1.21% |
| GGIZX | Balanced Allocation Fund | 0.98% |
| NMAVX | Nuance Mid Cap Value Fund | 0.81% |
| JGLO | JPMorgan Global Select Equity ETF | 0.47% |
| IXJ | iShares Global Healthcare ETF | 0.40% |
| PRPQX | PGIM Jennison Energy Infrastructure Fund | 1.10% |
| IGLGX | Columbia Select Global Equity Fund | 1.22% |
| URTH | iShares MSCI World ETF | 0.24% |
| IGFAX | VY(R) MORGAN STANLEY GLOBAL FRANCHISE PORTFOLIO | 1.21% |
| FEIKX | Fidelity Equity-Income Fund | 0.46% |
| SCGVX | Sands Capital Global Growth Fund | 1.21% |
| HFCVX | Hennessy Cornerstone Value Fund | 1.22% |
| BFGUX | Baron Focused Growth Fund | 1.05% |
| HFCSX | Hennessy Focus Fund | 1.49% |
| FVD | First Trust Value Line Dividend Index Fund | 0.61% |
| FIQOX | Fidelity Worldwide Fund | 1.06% |
| EICCX | EIC Value Fund | 1.96% |
| GABAX | The Gabelli Asset Fund | 1.33% |
| SOPAX | ClearBridge Dividend Strategy Fund | 1.00% |
| JETS | U.S. Global Jets ETF | 0.60% |
| DVIPX | DAVENPORT VALUE & INCOME FUND | 0.86% |
| PXWEX | Impax Ellevate Global Women's Leadership Fund | 0.77% |
| IGHAX | Voya Global High Dividend Low Volatility Portfolio | 1.10% |
| DGLAX | BNY Mellon Global Stock Fund | 1.22% |
| AAOTX | American Funds 2065 Target Date Retirement Fund | 0.73% |
| GAMPX | Goldman Sachs Energy Infrastructure Fund | 1.11% |
| PLTAX | Principal LifeTime 2060 Fund | 1.20% |
| APDMX | Artisan Mid Cap Fund | 1.05% |
| IOO | iShares Global 100 ETF | 0.40% |
| ARKF | ARK Fintech Innovation ETF | 0.75% |
| FETKX | Fidelity Equity Dividend Income Fund | 0.46% |
| MAGEX | MFS Growth Allocation Fund | 1.19% |
| FBTAX | Fidelity Advisor Biotechnology Fund | 1.71% |
| REET | iShares Global REIT ETF | 0.14% |
| FSPCX | Select Insurance Portfolio | 0.69% |
| APDTX | Artisan Focus Fund | 1.15% |
| PFLJX | Principal LifeTime 2050 Fund | 0.88% |
| SASDX | SAAT Aggressive Strategy Fund | 1.99% |
| TTFIX | Nuveen Lifecycle 2045 Fund | 0.68% |
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